biodesyn
Science  ·  Strategy  ·  Business Acumen
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Biopharma executive  ·  Scientific advisory  ·  Lausanne

The decisions that shape a pipeline are rarely purely scientific.

biodesyn is the consulting practice of Daphné Truan, R&D director, and biopharma strategist with twenty years building and advancing biologics and vaccine programs across Janssen, Lonza, and GSK. I partner with teams at the moments that matter: when pipelines need direction, when assets require hard decisions, and when science must translate into outcomes that hold up commercially and operationally.

Three interlocking dimensions

Science

The molecular-level foundation for pipeline decisions that stick. From target tractability and protein engineering to developability and go/no-go advisory, grounded in two decades of hands-on work across biologics and vaccines.

Strategy

Portfolio direction, cross-functional alignment, and program leadership from early discovery through NME declaration. Translating scientific progress into organisational outcomes that hold under pressure.

Business Acumen

Governance, financial oversight, and board-level judgement, with the commercial literacy to sit in resource allocation discussions as a peer.

What we do

Where biodesyn operates

I take on a limited number of engagements. Most sit at the strategic level, but I stay close to the work: program leadership, pipeline decisions, and building the scripts or workflows teams need when operational efficiency matters.

Scientific Advisory

Target selection, protein design, developability strategy, AI/ML integration, and pipeline prioritisation for biologics and vaccine programs.

Pipeline Leadership

Program leadership, cross-functional coordination, stage-gate advisory, and translational strategy from discovery through preclinical milestones.

Organisational Strategy

Function-building, team performance, Disciplined Agile implementation, cross-functional alignment for R&D environments, and hands-on workflow or automation work when teams need practical tools to move faster.

Governance and Board Roles

Independent scientific judgement for boards and scientific advisory boards. R&D strategy audit, portfolio risk assessment, and financial oversight where deep pipeline expertise is relevant.

The SynMinds Series

A common language for high-performing teams.

Biology, computation, and operations teams often use different mental models, and that slows decisions down. I built the SynMinds Series as short reference materials for cross-functional teams: shared vocabulary and frameworks that make collaboration easier. They started as internal documents and are now available on request.

Antibodies Decoded

Foundations for Discovery & Development

AI Demystified

From Concepts to Applications

Disciplined Agile Unlocked

Frameworks for High-Performing Teams

Viral Vaccines Blueprint

Foundations for Discovery

Available upon request. Tailored versions for specific team contexts can be discussed.

Contact

Get in touch.

I work with a small number of clients at any one time and I am open to conversations about consulting engagements, CSO and VP R&D roles, and independent board or SAB mandates. If the timing is right, I would be glad to talk.

Email

Location

Lausanne, Switzerland

LinkedIn

linkedin.com/in/daphnetruan

linkedin.com/company/biodesyn

Confidentiality

biodesyn operates under strict confidentiality agreements and applies secure data-handling practices aligned with pharmaceutical industry standards.